Using SharePoint 2013;
Issue: We are getting the following error when the portal page is accessed.
"Cannot complete this action as the Secure Store Shared Service is not responding. Please contact your administrator."
Cause: Secure store service is not running or not set with proper permission.
Resolution: In IIS, change the secure store service Application pool identity to a dedicated user if it is pointed to Network service/Local Service.
Because Secure Store is used to store sensitive information, for better security run the Secure Store Service in a separate application pool that is not used for any other service.